Sevoflurane during the perfusion period of the open heart surgery
Abstract
The paper reviews the randomized uncontrolled investigations involving 250 patients aged 47 to 65 years old undergone coronary artery bypass surgery or cardiac valve replacement and provides data on the application of inhalation anaesthetic Sevoflurane during the assisted circulation. Applying Sevoflurane allows preventing negative effects of the intravenous anaesthetics on the myocardium likely to be observed after the cardiac resuscitation when the hemodynamics is stabilized by the cardiac output, and the anaesthetic drug known to have the least cardiodeppresive effect is more preferable. In case of Sevoflurane, more rapid post-anaesthesia recovery of the central nervous system ensures early activization of patients and decrease of artificial lung ventilation period.
About the Authors
A. S. Khatinsky
Federal Centre of Cardiovascular Surgery
Russian Federation
Russian Federation
A. A. Foursov
Federal Centre of Cardiovascular Surgery
Russian Federation
Russian Federation
V. A. Sakovich
Federal Centre of Cardiovascular Surgery
Russian Federation
Russian Federation
References
1. Хатинский А.С., Бигашев Р.Б., Линев К.А., Назаров И.П. Способ применения анестетика севофлурана при опера циях аортокоронарного шунтирования и протезирования клапанов сердца у взрослых больных во время искусственного кровообращения // Патент на изобретение № 2309771, зарегистрирован в Государственном реестре изобретений Российской Федерации 10 ноября 2007 г.
2. Bouwman R.A., G. van’t Hof F.N., de Ruijter W. et al. The mechanism of sevoflurane-induced cardioprotection is independent of the applied ischaemic stimulus in rat trabeculae // Br. J. Anaesthes. 2006. Vol. 97, № 3. P 307-314.
3. De Hert S.G., F. Turani, S. Mathur et al. Cardioprotection with Volatile Anesthetics: Mechanisms and Clinical Implications // Anesthesia & Analgesia. 2005. Vol. 100. P. 1584-1593.
4. Dellinger R.P., Levy M.M., Carlet, J.M. et al. Surviving sepsis campaign guidelines for management of severe sepsis and septic shock // Critical Care Medicine. 2004. Vol. 32, No. 3. P. 858-873.
5. Ebel D., Preckel B., You A. et al. Cardioprotection by sevoflurane against reperfusion injury after cardioplegic arrest in the rat is independent of three types of cardioplegia // Br. J. Anaesthes. 2002. Vol. 88, No. 6. P. 828-835.
6. Frabdorf J., De Hert S., Schlack W. Anaesthesia and myocardial ischaemia/reperfusion injury // Br. J. Anaesthes. 2009. Vol. 103, No. 1. P. 89-98.
7. Kennedy R.R., Minto C., Seethepalli A. Effect-site half-time for burst suppression is longer than for hypnosis during anaesthesia with sevoflurane // Br. J. Anaesthes. 2008. Vol. 100, No. 1. Р 72-77.
8. Kitahata H., Nozaki J., Kawahito S. Low-dose sevoflurane inhalation enhances late cardioprotection from the anti-ulcer drug Geranylgeranylacetone // Anesthesia & Analgesia. 2008. Vol. 107, No. 3. P. 755-761.
9. Lutz M., Liu H. Inhaled Sevoflurane produces better delayed myocardial protection at 48 versus 24 hours after exposure // Anesthesia & Analgesia. 2006. Vol. 102. P. 984-990.
10. Piriou V., Mantz J., Goldfarb G. et al. Sevoflurane preconditioning at 1 MAC only provides limited protection in patients undergoing coronary artery bypass surgery: a randomized bi-centre trial // Br. J. Anaesthes. 2007. Vol. 99, No. 5., P. 624-631.
11. Riess M.L., Novalija E., Camara A.K. et al. Preconditioning with sevoflurane reduces changes in nicotinamide adenine dinucleotide during ischemia-reperfusion in isolated hearts: reversal by 5-hydroxydecanoic acid // Anesthesiology. 2003. Vol. 98, No. 2. P. 387-395.
12. Roesslein M., Frick M., Auwaerter V. Sevoflurane-mediated activation of p38-mitogen-activated stresskinase is independent of apoptosis in jurkat T-cells // Anesthesia & Analgesia. 2008. Vol. 106, No. 4. P. 1150-1160.
Review
For citations:
Khatinsky A.S., Foursov A.A., Sakovich V.A. Sevoflurane during the perfusion period of the open heart surgery. Pacific Medical Journal. 2012;(4):29-31. (In Russ.)
Views:
202
Email this article 