Dependences between the densities of cholinergic innervations on the middle cerebral artery of vertebrates, its diameter and middle membrane thickness

Abstract

The paper offers the method of approximating the reference-point dependence between two variables to estimate dependences between the medial cerebral artery of the vertebrates, thickness of its middle membrane and density of effectory innervations. The authors have examined bony fish, amphibians, reptiles, birds and mammals, determined the cholinergic nerve fibres by Kelley’s histochemical method on acetylcholinesterase on the total preparations, and calculated the density of nerve plexuses at 1 mm of the vessel surface. As reported, the density of the cholinergic innervations increases in parallel to the increase of the artery diameter and thickness of its middle membrane. The cholinergic innervations of the middle cerebral artery intensify from lower vertebrates to superior vertebrates, and reach their maximum in mammals.