Present-day ideas on pathogenesis of pain
Abstract
The paper provides an overview of the literature about the current pathophysiological and neurochemical aspects of pain generation and considers the matters relative to the role of glutamate receptors, nitrogen oxide, inflammation mediators, collateral sprouting, phenotype switchover phenomenon, and other mechanisms in the pain generation. The authors set out the up-to-date ideas about the role of genome in generating the pain syndrome, and prospects for the further researches.
About the Authors
T. V. Balashova
Vladivostok State Medical University
Russian Federation
Russian Federation
N. A. Andreeva
Vladivostok State Medical University
Russian Federation
Russian Federation
L. A. Mnatsakyan
Vladivostok State Medical University
Russian Federation
Russian Federation
A. G. Kotelnikova
Vladivostok State Medical University
Russian Federation
Russian Federation
A. M. Dolgunov
Vladivostok State Medical University
Russian Federation
Russian Federation
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Review
For citations:
Balashova T.V., Andreeva N.A., Mnatsakyan L.A., Kotelnikova A.G., Dolgunov A.M. Present-day ideas on pathogenesis of pain. Pacific Medical Journal. 2012;(3):13-16. (In Russ.)
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