Application of system analysis for evaluation of significance of changes of nitroxidergic neurons in nucleuses of rats’ medulla in case of experimental hypertension

Abstract

The experiment with rats was used to study options for applying methods of system analysis (pair correlation, grade correlation and regression) to evaluate interrelation between quantity of nitroxidergic neurons with various activity of NADPH-diaphorase in the medulla nucleuses and value of arterial pressure. Although the methods recommended were only the private case of applying the statistical analysis of results in biological studies, they allowed evaluating the many-valuedness of interrelations existing between changes of diaphorase activity in the medulla nucleuses and variations of arterial pressure. The programs of correlation and regression helped to determine the most ponderable changes of the factor in reticular gigantocellular nucleus and dorsal nucleus of nervus vagus. The grade correlation program allowed finding the most ponderable changes in dorsal nucleus of nervus vagus and reticular small-cell nucleous.