The review is devoted to rehabilitation medicine as a component of a new policy in the field of public health of the Russian Federation. Necessity of development of this direction is emphasized within the priority national project "Zdorov'e (Health)". Problems of the infrastructure development of rehabilitation medicine are discussed and especially its sanatorium part. The place of the medical rehabilitation centers in structure of pre-hospital and hospital medicine is determined, as well as the role of experts at the valeology-ecological and specialized stages.

This article presents an evidence based analysis of efficacy of physiotherapeutic techniques. It characterizes a basic structure of this clinical study and covers principles of critical analysis of literature sources related to physiotherapeutic treatment techniques.

This is an analytical review, in which the questions of a modern status of rehabilitation medicine in Russia and in the Far East are discussed. The special importance of preventive programs in improvement of health of the population, health protection of healthy people is emphasized. The accent on lo-al improving resources, including natural factors of sanatorium "Sinegorskie Mineralnye Wody" is done. On the basis of the branch program and the Concept of public health of the Russian Federation the goals of creation of a regional infrastructure of rehabilitation in Primorye Territory are discussed.

According to the modern views one of the most important factors influencing the outcome of cardiovascular complications of arterial hypertension is the degree of the endothelial dysfunction. The majority of available data are devoted to an estimation of the medications actions. Authors studied the functions of the vascular endothelium according to the rate of the nitric oxide metabolits in plasma at 82 patients with arterial hypertension at including the ozone therapy in basic treatment. The control group included 20 healthy people. There was the initial evaluation, than — next evaluation in 7 days (3 ozone therapy procedures), in 1 month (7 ozone therapy procedures) and in 6 months of treatment. It is found, that using of the ozone therapy in the complex treatment of arterial hypertension of grade I and II improves the outcomes. It is shown in earlier normalization of parameters of arterial pressure, restoration of the metabolic activity of the vascular endothelium due to the increasing of the plasma nitric oxide rate, and it gives stable good outcomes revealed in 6 months of research.

To estimate the role of bio-elements in pathogenesis of pneumonias the contents of Al, B, Ba, Ca, Cr, Cu, Mg, Mn, Fe, Na, Sr, Zn in the condensate of exhaled air at 40 patients and 102 healthy men in the age from 18 till 23 years is determined. Dominating bio-elements were sodium, calcium and magnesium. In the case of acute inflammation in the lungs the concentration of all bio-elements in a condensate considerably decreased, especially the levels of chromium, copper and strontium. During the reduction of pneumonia partial restoration of element structure testified the incomplete rehabilitation of metabolic changes in the lungs. Between the activity of system «peroxide oxidation of lipids — antioxidant protection» and the levels of bio-elements the correlations of a various degree of intensity are found. The interrelation between the contents of lipoperoxidation products and a complex of the elements with antioxidant functions — copper, manganese, zinc, calcium is the most interesting.

With the purpose of studying of the epidemiology of the mineral dysbalance in children and teenagers — inhabit- ants of the modern industrial center— authors examined 1450 almost healthy residents of Vladivostok in the age of 3 — 16 years. The method of the atom-absorption spectrometry was used to evaluate the rate of Pb, Cd, Cr, Mn, Cu, Zn, Fe, Ca, Mg. The prevalence of surplus and deficiency of mineral substances is investigated. With the help of the step-by-step discriminant analysis the risk factors of the element homeostasis dysbalance are investigated and the algorithm of the forecast of changes of the element status is developed.

The method of serial cultivations is used to investigate the resistency to antibacterial agents of 21 pneumococci stains cultivated of induced spit of pneumonia patients. Streptococcus pneumoniae had high sensitivity to amoxicilline/clavulanate, ceftriaxone, linezolide, rifampycin, and vancomycin. Macrolides had low antipneumococcal activity. 28.6% of the pneumococci stains were resistant to trovafloxacin. The method of polymerase chain reaction in 71.6% of cases could determine the genes of resistency mefE, mefA, ermB and ermA to macrolides and in 61.9 % of cases — genes gyrA, gyrB, parC and pare to ftorchinolones.

98 patients with chronic obstructive pulmonary disease were inspected in during 2 years. Standard electrocardiogram, computer electrocardiotopogram, ultrasonic cardiography have been executed to all patients for the period of supervision. Diagnostic criteria of right heart hypertrophy have been revealed with using of computer electrocardiotopography method. Advantage of computer electrocardiotopography method in comparison with standard electrocardiogram and ultrasonic cardiography methods were shown for revealing of chronic pulmonary heart in patients with chronic obstructive pulmonary disease.

86 healthy teenagers (52 boys and 34 girls) in the age from 15 till 20 years old with the help of tracheophonography of the forced exhalation with the evaluation of the duration of the tracheal noise are surveyed. Three subgroups with average duration of noise 1.12-1.50, 0.70-1.12 and 1.50-2.09 sec were found. The moderate correlation between the time of fixing of noise with spirometric and some anthropometrical parameters is found. After the pharmacological test with salbutamol the group of healthy teenagers (29.1%) with the changed reactivity of respiratory ways is allocated.

Authors estimated the role of the antiinflammatory cytokine IL-10 and regulator cytokine IL-12 in the development of pneumonia in 53 patients after aorto-coronary bypass. In the patients with a postoperative pneumonia the increased blood level of IL-10 before the surgery, and in 1 day after surgery the decrease in the ratio IL-12p70/IL-12p40 and excessive growth of secretion of IL-10 is revealed, and also the decrease in the mitogen-activated secretion of IL-10 by blood cells and the decrease in the index of activation of cells to IL-12 production is found. The revealed abnormalities determine the necessity of immunotrope therapy to this category of patients.

The main aspect in treatment of the patients with chronic obstructive pulmonary disease (COPD) is the detecting of the progressing bronchoobstruction (BO). The detecting of BO is carried out by such well-known methods as spirography and peakflowmetry. Some investigators emphasized insufficient evidence of these methods that is connected with subjectivism under realization of the research. The up-to-date methods must be objective, uninvasive, economical and easy. One of such methods is the computed dermography (CD-method) developed in Primorsky region and recommended by the Department of Health for application in medical practice. From the beginning of 2004 in Russia the new preparation of anticholinergic group of prolonged action — tiotropium bromide was registered. The purpose of this research was a clinicial-functional estimation of the efficiency of the tiotropium bromide (activity cholinergic receptors) in the patients with COPD of the CD-method of the function F5-3. 20 patients with COPD III-IV stages with clinical manifestations of the COPD has been had necessary therapy according to the stage of weight were observed in Regional pulmonary center. So, the CD-method was determined to be an objective and more sensitive method which allows detecting of the BO's progressing and prognosticate it in the patients with COPD after the long treatment tiotropium bromide.

The results of clinical-laboratory examination of 801 soldiers of the first six months of service in the army who were treated in the Pulmonology Department of Pacific Fleet Navy Hospital from 1999 to 2004 concerning acquired pneumonia are shown. Some new, informative and objective signs of pneumonia which can be used for early diagnostics of illness and adequate treatment are discussed.

The authors have examinated of 364 young patients with community-acquired pneumonia at the age of 17—23 have been carried out. There were 249 patients with ICDS. There were performed clinical examinations, spirography, ECG, echocardiography in the time of admission and in the time of discharge. It is showed, that in group of the patient with ICDS pneumonia has more serious and longer course. These patients have complications like: infectionally-toxical stress, miocarditis more often. The changes from the side of cardiovascular and respiratory systems have more expressive character. The treatment becomes more expensive.

Authors investigated the metabolic functions of lungs at patients with the opioid drug dependence. Significant changes of metabolic processes which can predict the developing of respiratory pathology are revealed. For the prophylaxis of this condition in the postabstinent treatment the authors suggested the nebulaiser therapy with the extract of the root of Glycerrhiza Uralensis. The results of therapy have shown the efficiency of correction of metabolic changes in a pulmonary tissue.

55 cases of pneumonia with the background of long alcoholic and drug addiction, at patients in the age of 23—45 years are investigated. It is established, that at this category of patients the pneumonia is characterized by severe symptoms, more often purulent complications, septic endocarditis and the toxic shock. Among the microorganisms causing the disease it is possible to allocate the mixed and opportunistic infections, and also fungi infections, correlated with a secondary immunodeficiency. One of the important reasons of severeness of the diseases and lethal outcomes should be the late hospitalization caused, in particular, by proceeding of taking of the alcohol and drugs.

The aim of study was to investigate the apoptotic and necrotic index of induced sputum cells in different periods of bronchial asthma and under corticosteroids therapy. The authors have examined 70 patients suffering from bronchial asthma and 30 healthy voluntaries of the same age and sex. They used the fluorescent microscopy method of induced sputum cell sediment. During exacerbation of asthma the intensification apoptotic activity, increase of survive and necrotic lymphocytes and neutrophiles amount were founded. These change returned to norm in remission and under application of corticosteroid therapy. When authors studied types of cell death in different periods of asthma it was founded that the necrotic index prevails over apoptotic index. During exacerbation of asthma these data were almost identical.

The purpose of the research is to do a comparative analysis of staphylococcus alpha-toxin elimination from different purulent-necrotic inflammatory focuses in lungs and pleura. The experiment on 36 rabbits allowed us to develop methods for simulating these inflammations. It was found that microbe toxins reabsorb from purulent-necrotic inflammations in lungs and pleura, mainly through lymphatic route.

The original technique of bronchography with computer data processing is described. On a material of 145 clinical and 45 control group patients in the age of 7—17 years the high sensitivity (85%) and specificity (93%) of the methods is shown. Authors recommend bronchography for primary pre-radiologic method for revealing the local lesions in lungs.

The analysis of morbidity and mortality in prison system of Primorsky Region in 1986—2005 is resulted. It is shown, that the structure of mortality among the prisoners differs much from the mortality in general population. The most part of died was at working age (30—50 years old). Among the causes of death the tuberculosis and other infectious diseases were registered more often.

On the basis of clinical (172 patients) and morphological (the material of 50 autopsies) material it is found, that the ratio of male with oppressed spermatogenesis in the fertile age population of Primorski Krai prevails on male with the normal spermatogenesis. It is obvious, that the received data reflect the common process of decrease spermatogenic human functions, which is found all over the world.

An ability of calcium alginate to bind the immunoglobulin with hialuronidaze in water solution is investigated depending on time, concentration and pH of the solution. The protein adsorption been described by the Langmuir equation. Absorption balance was found in 180 minutes for immunoglobulin and in 30 minutes for hialuronidase. Values of the maximal sorption capacity and dissociaton constants were for immunoglobulin 750 mg/g and 1.6 mg/ml, and for hialuronidase 475 mg/ g and 1.4 mg/ml, respectively. The adsorption of immunoglobulin was maximal at pH 6, and hialuronidase — pH 7.

For the whole analysis of teenagers' criminal aggressive behavior it is necessary to observe the peculiarities of the personality as well as the situation in which the crime was held. The types of the aggressive behavior are divided into pathological on the one hand and non-pathological on the other; and have its' classification. All above mentioned is necessary to take into consideration while analyzing the teenagers' criminal behavior.

The dependence of the color perception of the rhythmic photic stimulations on the psychophysiological state was studied. It was revealed, that color perception of rhythmic photic stimulations dependens on disorders of interrelations between cortex and subcortex, instability of neurodynamic processes, predominance of excitation in the central nervous system, emotional state and personality peculiarities. The results have the theoretical significance for the study of the color perception mechanisms.

The model of scheduled hospitalization of patients in Hospital for Veterans of Wars, developed by authors is described. Due to the created program patients of a preferential category of all cities and areas of Primorski Krai (the Hospital works as regional medical institution) have been taken into the list. On the basis of beforehand widespread permits at the time of the admitting it was possible to provide the admitting according to the profile and sequence of hospitalization of patients (in the day of discharge on this free place it was possible to take a new patient). All this has allowed to supervise the amount of beds, to analyze the parameters of work of a hospital in dynamics, to make the conclusions and to correct the program as required, and also to observe the continuity between medical institutions.

Conceptually the process of teaching the questions concerning the role of environmental factors in the human surviving abilities is considered in our University not only in ecologic-hygienic, but also ecologic-clinical interpretation. As a whole, the teaching of ecology of the human should be practiced from the position of the structural — systemic approach concerning the goal of the objective, comprehensive and on various levels estimation the role of environmental factors and the organism homeostasis, to predict the health of a society, to form a healthy way of life. The education of students from these positions will allow preparing ecologically competent doctors for all the areas of practical public health services.

The problem of a subject and method of knowledge and intervention of clinical psychology in comparative aspect with a subject and a method of knowledge and intervention of psychiatry is studied. This attempt is undertaken to present schematically the distinctions in the professional work of the clinical psychologist and the psychiatrist.

In 2002 in the Sakhalin base medical college the complex program on health-preserving educational space has been developed. Within this program at regional exhibition MedINFO students of college had provided the action «Learn your blood pressure». During the questioning of the participants and visitors of an exhibition the data confirming a role of major risk factors in the genesis of the arterial hypertension has been received.