JUSTIFICATION FOR IMMUNOTROPIC THERAPY DURING CONGENITAL PNEUMONIA DIAGNOSED IN NEWBORN CHILDREN

Abstract

The paper describes results of studies of system of cytokines and a1-acid glycoprotein carried out for 60 new-born children suffered from congenital pneumonia, within the first 3 days of their lives. It has been revealed that imbalance of immunologic mechanisms of new-born children having congenital pneumonia is accompanied by decrease in neutrophil inflammatory responses, manifests in low level of interleukin-8 and ineffectiveness of protective and adaptive cell functions. Applying of Viferon-1 as a part of complex therapy allowed the survival rate for new-born children having severe manifestations of disease to increase as well as the intensive care to be optimised, the periods of treatment to shorten and the detected immunologic imbalance to be resolved in due time.