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SYSTOLIC AND PULSE PRESSURE IN AORTA IN COMBINED CARDIORESPIRATORY PATHOLOGY

Abstract

The paper describes systolic and pulse pressures in aorta, their relationship with peripheral arterial tension and basic characteristics of aorta rigidity, which have been observed in 60 patients suffered from chronic obstructive lung disease coupled with chronic coronary heart disease. The result of treatment is 30 healthy patients. The authors have applied a method of noninvasive arteriography and evidenced an increase in aortal systolic and pulse pressure and decrease in compliance of great blood vessels during the 1st and 2nd stages of chronic obstructive lung disease. The findings substantiate a correlation between increase of central and peripheral arterial tension and basic characteristics of aorta rigidity. The 3rd stage of chronic obstructive lung disease included "paradoxical" decrease in central and peripheral arterial and aortal pulse pressures. Among the more sensitive elastance indices of great blood vessels and myocardium are augmentation index, difference and affinity index of central and peripheral systolic pressure, relationship between indices of cardiac cycle area, and interval of left ventricle ejection period. The markers specified above may be used to evaluate the degree of cardiovascular risk in case of combined cardiorespiratory pathology.

Keywords


616.12-008.331/.351:616.132]:[616.12-005.4+616.233-002-036.12

About the Authors

В. Невзорова
Владивостокский государственный медицинский университет
Russian Federation


О. Шекунова
Владивостокский государственный медицинский университет
Russian Federation


О. Голотина
Владивостокский государственный медицинский университет
Russian Federation


Т. Бродская
Владивостокский государственный медицинский университет
Russian Federation


V. A. Nevzorova
Vladivostok State Medical University
Russian Federation


O. I. Shekunova
Vladivostok State Medical University
Russian Federation


O. V. Golotina
Vladivostok State Medical University
Russian Federation


T. A. Brodskaya
Vladivostok State Medical University
Russian Federation


References

1. Гельцер Б.И., Бродская Т.А. Результаты исследования центрального артериального давления у больных хронической обструктивной болезнью легких // Терапевтический архив. 2008. № 3. С. 15-19.

2. Моткина Е.В., Невзорова В.А. Функциональное состояние сосудистого эндотелия и хроническое воспаление при ХОБЛ // Тихоокеанский мед. журнал. 2005. № 2. С. 34-37.

3. Ahmed Q., Alberto A. et al. Determination of aortic pulse wave velocity from waveform decomposition of the central aortic pressure pulse // Hypertension. 2008. Vol. 51. P. 188.

4. Arteriograph TensioClinic and its program TensioClinic. User's manual // Early diagnosis of arteriosclerosis. URL: <http://www>. tensiomed.com/eng/tclin <http://tensiomed.com/eng/tclin> (дата обращения 20.06.2009).

5. Falk J.A., Kadiev S., Criner G.J. et al. Cardiac disease in chronic obstructive pulmonary disease // Proceedings of the ATS. 2008. Vol. 5, No. 4. P. 543-548.

6. Francesco A.C., Scipione C., Vitantonio D.B. et al. Arterial stiffness and ventricular stiffness: a couple of diseases or a coupling disease? A review from the cardiologist>s point of view // European Journal of Echocardiography. 2009. Vol. 10, No. 1. P. 36-43.

7. Franklin S., Khan S. et al. Is pulse pressure useful in predicting risk of coronary heart-disease? The Framingham Heart Study // Circulation. 1999. Vol. 100. P. 354-360.

8. Laurent S., Cockcroft J., Van Bortel L. et al. Тhe European network for non-invasive expert consensus document on arterial stiffness: methodological issues and clinical applications // Eur.

9. Heart J. 2006. Vol. 27, No. 21. P. 2588-2605.

10. Noma K., Goto C., Nishioka K. et al. Roles of rho-associated kinase and oxidative stress in the pathogenesis of aortic stiffness// J. Am. Coll. Cardiol. 2007. Vol. 64. P. 1016-1021.

11. Sabit R., Bolton C.E., Edwards P.H. et. al. Arterial stiffness and osteoporosis in chronic obstructive pulmonary disease // Am. J. Respir. Crit. Care Med. 2007. Vol. 175, No. 12. P. 1259-1265.

12. Sin D.D., Wu L., Man S.F.P. The relationship between reduced lung function and cardiovascular mortality: a population-based study and a systematic review of the literature // Chest. 2005. Vol. 127, No. 6. P. 1952-1959.

13. Sleight P., Yusuf S., Pogue J. et al. Blood-pressure reduction and cardiovascular risk in HOPE study // Lancet. 2001. Vol. 358. P. 2130-2131.

14. The CAFE Investigators, for the Anglo-Scandinavian Cardiac Outcomes Trial (ASCOT) Investigators CAFE Steering Committee and Writing Committee Differential Impact of Blood Pressure-Lowering Drugs on Central Aortic Pressure and Clinical Outcomes Principal Results of the Conduit Artery Function Evaluation (CAFE) Study // Circulation. 2006. Vol. 113. P. 1213-1225.

15. Veronica Rolim S.F., Joseph F.P., Susan C. et al. Arterial stiffness is associated with regional ventricular systolic and diastolic dysfunction // Arteriosclerosis, Thrombosis, and Vascular Biology. 2008. Vol. 28. P. 194.

16. Weber T., Auer J., O'Rourke M.F. et al. Prolonged mechanical systole and increased arterial wave reflections in diastolic dysfunction // Heart. 2006. Vol. 92. P. 1616-1622.


Review

For citations:


 ,  ,  ,  , Nevzorova V.A., Shekunova O.I., Golotina O.V., Brodskaya T.A. SYSTOLIC AND PULSE PRESSURE IN AORTA IN COMBINED CARDIORESPIRATORY PATHOLOGY. Pacific Medical Journal. 2009;(4):55-59. (In Russ.)

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ISSN 1609-1175 (Print)