Prospects of application of DNA‑vaccines in preventive maintenance of the hantaviral infection
Abstract
DNA-vaccination methods are based on the introduction of plasmid DNA encoding the pathogen's protein to organism. This approach allows obtaining the complete immune response to different bacterial and viral antigens. At the review, perspective is considering of DNA-vaccine creation on the base of HFRS-exciting structural genes, and problems following such a vaccines creation are emphasized.
About the Authors
O. V. Chubukova
Institute of Biochemistry and Genetics, Ufa Research Center, Russian Academy of Sciences
Russian Federation
Russian Federation
Yu. M. Nikonorov
Institute of Biochemistry and Genetics, Ufa Research Center, Russian Academy of Sciences
Russian Federation
Russian Federation
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Review
For citations:
Chubukova O.V., Nikonorov Yu.M. Prospects of application of DNA‑vaccines in preventive maintenance of the hantaviral infection. Pacific Medical Journal. 2008;(2):37-40. (In Russ.)
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