Effect of the severity of community-acquired pneumonia on the course and outcomes of acute coronary syndrome
https://doi.org/10.34215/1609-1175-2026-1-72-76
Abstract
Objective: To evaluate the impact of the severity of community-acquired pneumonia (CAP) on the clinical and functional characteristics, course, and outcomes of acute coronary syndrome that developed in the context of CAP. Materials and methods. A retrospective observational study with a case-control design element was conducted on 90 patients with acute coronary syndrome (ACS) and a history of CAP. Results. Regression analysis models revealed that hypoxemia (SpO2 <90%), fibrinogen, troponin T, hemoglobin, and blood platelet levels, in combination with pneumonia severity and serum C-reactive protein (CRP), significantly impact tricuspid regurgitant jet velocity (TRJV), explaining 83.5% of its variability. The risk of paroxysmal atrial fibrillation increased with higher TRJV, greater pneumonia severity, and diuretic use. Conclusion. In patients with ACS combined with CAP, the role of hypoxemia and biological markers of inflammation in the development of right ventricular heart failure and paroxysmal atrial fibrillation has been established.
About the Authors
M. E. Tseimakh
Altai State Medical University
Russian Federation
Russian Federation
Barnaul
E. F. Kotovshikova
Altai State Medical University
Russian Federation
Russian Federation
Barnaul
I. A. Sukmanova
Altai State Medical University; Altai regional cardiology dispensary
Russian Federation
Russian Federation
Barnaul
E. G. Nikulina
Altai regional cardiology dispensary
Russian Federation
Russian Federation
Barnaul
I. Ya. Tseimakh
Altai State Medical University
Russian Federation
Russian Federation
Irina Ya. Tseimakh - Dr. Sci. (Med.), Associate Professor, Head of the Department of Pulmonology and Phthisiology with a course of postgraduate education, Altai State Medical University.
40 Lenin ave., Barnaul, 656038
tel.: +7 (385) 256-69-64; +7 (909) 505-35-37
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Review
For citations:
Tseimakh M.E., Kotovshikova E.F., Sukmanova I.A., Nikulina E.G., Tseimakh I.Ya. Effect of the severity of community-acquired pneumonia on the course and outcomes of acute coronary syndrome. Pacific Medical Journal. 2026;(1):72-76. (In Russ.) https://doi.org/10.34215/1609-1175-2026-1-72-76
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