The review of the literature devoted to age-sexual and regional features of teethng of constant teeth as the important indicator of a biological maturity and a state of health of children, necessary at planning and realization of schemes and actions of programs of prophylaxis of the defects of biological development among the pediatric population. Modern methods and approaches for an estimation of criteria of a tooth maturity of the child are presented. Works of Russian and foreign authors on secular trend are estimated, these researches were done in Europe, Russia, Asian and the North American countries. Features of teething of constant teeth in the different conditions of inhabitancy, training and education are evaluated. The results of last researches of the teething in children and the teenagers living in various regions of the Russian Federation and also in the countries of near and far abroad are resulted.

The critical analysis of the experimental trauma model and the state of the cells of the mucous membrane of the rat maxillary sinus is presented. The data about apoptosis and its regulation at cutting of the maxillary nerve and skull bones fracture are shown. The presence of the specific pattern of an expression of molecular apoptosis factors and their roles in regeneration and tissue growth is shown. This approach allows considering the state of the injured mucous membrane in general and different cell types depending on the level of their apoptotic death.

The review of the literature devoted to a problem of stomatologic disease of children with different level of mental retardation, living in the territory of the Russian Federation. Authors conclude about the presence of some features of prevalence and intensity of pathology of teeth solid tissue and parodontal diseases, and also a hygienic state of the oral cavity at whole in this category of patients. At children-invalids with mental retardation the combination of several kinds of a stomatologic pathology (carious teeth, parodontitis, maxillofacial and dental anomalies and deformations) was observed at high prevalence of maxillofacial and dental diseases which mutually aggravate the clinical course and complete the unsatisfactory hygiene of an oral cavity.

Background. Now “the gold standard” for estimating the amount of fat in the organism are radiological absorbtiometry, the magnito-resonance tomography and computer tomography. However these methods have some disadvantages limiting their application in pediatric practice. The method of bioimpedancometry is simple in use, noninvasive, safe. It allows controlling the state of lipid, protein and water exchange and is one of tools of diagnostics and an estimation of efficiency of treatment of the obesity. Methods. Complex exam of 542 children at the age from 7 till 17 years of the I and II groups of health was done. For the quantitative estimation of structurally-corporal components of the organism the device “DIAMANT-AIST” was used. Results. The criteria of average (normal), under and over the average indexes of the bioimpedansometry are developed by the multilateral logarithmic regress. The corrected relation of probable possibilities with 98 % confidential interval is counted. In the case example the personified approach to the estimation of physical development is presented. Conclusions. The individual approach to the use to correction of physical retardation of children of school age under the method of bioimpedansometry allows more precisely, depending on the revealed deviations of the body weight, to suggest the correction and prophylaxis. The developed tables of confidential intervals of bioimpedansometry indicators can be used by pediatricians, general practitioners and dieticians at the estimation of physical development in children and teenagers.

Background. The requirements of stomatologic practice and progress of medical materials technology determine the high intensity of experimental researches of new materials and technologies in the area of dental implantology. Methods. In the experiment of putting the screw titanic implants in femurs of rats in 4, 8 and 12 weeks the radiological, mechanical and morphological characteristics of the osteointegration zone have been studied. Results. On roentgenograms on 4th week of the experiment the circle osteointegration zone was visible. At morphological study the thin layer of the friable connecting tissue with the osteogenic centers was found. In12^th week osteointegration was finished: around the titanic implants the solid lamellar cover with sponge bone islets was found. Conclusions. General positive dynamics of osteointegration together with osteoconductive effect testified favouroubly the adequacy of the chosen experimental model. The small number of correlations between some indicators of the research methods was the basis for the recommendation of their use only in a complex: radiological research with radial densitometry of the osteointegration zone, mechanical study of the implant mobility and the classical morphological research added by the analysis of zone distribution of density of the organic matrix in the osteointegra-tion zone.

Background. Psychotropic preparations cause osteopenia and osteoporosis in mentally sick patients. Regional osteoporosis, absence of the regular oral cavity care - all these factors adversely affect parodont, considerably increase the risk of activisation of the infection. Dimephosphon is widely used in psychiatric practice as neurotropic vasoactivity medication having antihypoxic properties as a result of the improvement of the endocellular energy metabolism. Antirachitic action of this medication is described. Dimephosphan rises the calcitonin level as well as endogenic cortisol, stimulates regeneration processes, has anti-inflammatory and immune modulating activity. Methods. 64 patients of a psychiatric hospital taking neuroleptics and antidepressive agents for more than 3 years were examined. All patients have been divided on two groups - accepting dimephosphon as a part of pharmacotherapy for more than 6 months and second - never receiving this medication. The control group - mentally healthy people with parodont diseases. The analysis of the microelement status of a bone tissue of an alveolar processus and teeth by the method of atom-absorption spectrophotometry was done. Results. Mentally sick patients have high prevalence of chronic generalized parodontitis of moderate and severe degree. The low concentrations of calcium, copper, zinc in the teeth and bone tissue and increase of the strontium level is revealed. Strong correlation between the zinc level in a bone tissue and long (more than 10 years) chronic generalized parodontitis is found. At the patients taking dimephosphon, the level of calcium and copper in a bone tissue was higher and the gums bleeding index was lower than in the patients group not taking dimephosphon. Conclusions. The positive influence of dimephosphon intake on the state of parodont tissues and microelement structure of a bone tissue allow recommending this medication in the treatment complex not only for the mentally sick patients, but also for the other patients with chronic generalized parodontitis.

Background. In the Russian Federation the inflammatory diseases of parodont are an actual problem representing not only medical but also a social problem. Methods. For epidemiological researches of parodontal inflammatory diseases the accounting and registration forms of stomatologic clinics were used. 943 railway workers were surveyed. The identification of the allocated cultures was done by the automatic analyzer ATB Expression (BioMerieux, France). Results. Among the patients with gingivitis women were predominant and among the patients with paradontitits and parodontosis, as well as in general - men dominated. Most often the infectious pathology of the parodont was diagnosed at the age of 41-50 years. Gingivitis was more often registered at the age of 20-30 years, and not found in men of 31-40 and 41-50 years, and paradontitits and parodontosis were diagnosed almost with identical frequency. Essential differences in frequency of etiologically significant pathogens among the patients of different age and gender were not revealed. Conclusions. Calling for the stomatologic help at later stages of infectious process in parodont leads to such diseases as paradontitits and parodontosis that are typical for aged people with no dependence on gender being the general problem of out-patient service in stomatology.

Background. Rather recently in psychology the term “emotional burning” became popular. It is known that the emotional exhaustion can lead to the deviations in somatic condition. The research objective was the estimation of influence of a psychoemotional condition on the stomatologic status of patients. Methods. 146 individuals of 25-57 years were examined. The level of emotional burning was diagnosed by V.V. Boiko’s technique. All patients underwent oral cavity exam on clinical (stomatologic indexes) and on laboratory data. The received data were processed by the methods of variation statistics. Results. Correlating to the strengthening of expressiveness of emotional burning the intensity of complaints to dryness and discomfort in a mouth increased, the secretory activity of salivary glands decreased, the inflammation severity of parodont tissues increased, the neutrophil ability to phagocytosis decreased. The degree of emotional burning correlated with the deterioration of oral cavity hygiene, deterioration in local immunity changes and the functional condition of the epithelial mucous cells. Conclusions. Formation of the emotional burning condition promotes the deterioration of the stomatologic status of patients.

Background. One of the possible ways of microbiocenosis correction at parodont inflammatory diseases is the treatment with the probiotic microorganisms. Methods. To 35 of 68 patients of 20-60 years old with chronic generalized paradontitis of mild and moderate severity level the treatment was contributed by the washing of the parodontal pockets by the probiotic “Euflorin L” (the main group). To the remained 33 patients (control group) standard washing of the oral cavity with the parodontal pockets irrigation by only 0.05 % chlorine hexidine solution was done. The level of the oral cavity hygiene was estimated by the standard stomatologic indexes. A state of local immunity was studied by the reaction of adsorption of microorganisms, phagocyte activity of leukocytes, the test with nitro blue tetrasolium, the index of the neutrophil activation and by the level of IGA in saliva. The exam was done before the treatment, in a week, 3 and 6 months after the treatment. Results. In a week after the treatment at all patients the state of oral cavity has essentially improved, but immunologic indicators have improved only in the main group. In 3 months in both groups the positive dynamics of clinical symptoms remained, but in the main group the increase of phagocyte index and level of secretory antibodies as well as the increase of the adsorption activity of the epitheliocytes is shown. In 6 months at patients who underwent parodontal pockets washing by euflorin L, the phagocyte activity of leukocytes has increased as well as the adsorption activity of the epithelial cells, but the level of the secretory antibodies in saliva remained almost the same. Conclusions. Probiotic medications with the alive not-lyophilized strains of the lactobacteria not only positively influence the clinical state of the parodont tissues reducing the inflammation expressiveness but also improve the level of the indicators of local immunity.

Background. There are experimental data about the possibility of use the herb extracts in the therapy of tumors. Methods. In experiment on mice analyzed influence of the extract of the Dandelion medicinal on metastasing of the intertwined tumors at removal of primary tumor and chemotherapeutic treatment. Results. The dandelion extract inhibited the metastasing after the removal of the tumor and also reduced the quantity of postoperative relapses. Increase of the antiblastomic activity of cyclophosphane at animals with intertwined Ehrlich adenocarcinoma, Lewis pulmonary carcinoma, В-16 melanoma and lung cancer-67 under the influence of a dandelion extract is revealed. Allocated from this plant water-soluble polysaccharides at adding in the chemotherapy scheme also increased the efficiency of cyclophosphane at mice with Lewis pulmonary carcinoma. Conclusions. Experimental data testify to perspective of the further study of the extract of dandelion medicinal as the substance of additional therapy of the malignant tumors.

Background. Recently the great interest is given to studying of bacteria Listeria monocytogenes in connection with its increasing role in perinatal and neonatal pathology, ability to cause severe forms of diseases, massive contamination and accumulation in food. Methods. The strains of L. monocytogenes allocated in the Far East and in the European part of Russia are used. Antigen properties of cultures were defined in linear reaction of agglutination by typical polyvalent and monovalent (1^st and 2^nd serotypes) Russian listeri-ous serum. Further serotyping was done by multiplex polymerase chain reaction (PCR). Results. The research done by the method of multiplex PCR have allowed to characterize the structure of populations of L. monocytogenes, than linear reaction of agglutination and to show the prevalence of epidemically important serotype 4b in the Far East. So, 39 from 52 cultures (75 %) of L. monocytogenes allocated in the Far East were 4b serovariant, 10 cultures - were 1/2а serovariant, 2 cultures - 1/2b serovariant and 1 culture - 1/2с serovariant. Among the isolated in the European part of Russia 7 of 17 cultures (41.2 %) were 1/2a serovariant, 5 cultures - 4b serovariant, 3 cultures - 1/2c serovariant and 2 cultures - 1/2b serovariant. Conclusions. By the use of the method of multiplex polymerase chain reaction the variety of the Listeria strains circulating in different geographical territories was shown, with the differentiation of epidemically significant and dangerous to the human clonal variants of the microorganism. This method can be used in practical and scientific works for differentiation and estimation of the variety of Listeria cultures.

Background. Now in the pharmaceutical market the considerable quantity of medicamentous complexes for treatment and preventive maintenance of parodontal diseases is presented. The research objective - comparison of the efficiency of treatment and cost at use of the stomatologic treatment-and-prophylactic complexes “Asepta”, “Vivax” and “Wood balm”. Methods. 106 patients of 20-35 years old with mild chronic generalized parodontitis depending on the used treatment-and-prophylactic complex have been divided into three groups. Treatment duration - 14 days. Control examinations were done in 7, 14, 60, 120 and 180 days after the treatment beginning. In all cases the index estimation of the parodont state and the estimation of the alkaline phosphatase, lactate dehydrohenase and phosphor lipase А2 activity levels in the gingival liquid were done. Calculated the ratio of expenses and efficiency. Results. In 7 days after the beginning of treatment at patients of all groups clinical improvement was shown. Level of hygiene of the oral cavity without authentic distinctions between groups has considerably raised and remained at good level till the end of the follow-up period. The most expressed positive dynamics and peak of treatment efficiency were noted at the patients using “Asepta”. Initial hyperactivity of enzymes was normalized during the follow-up period but was similar to control only at “Asepta” group. The maximum expenses for efficiency unit were 24.85 roubles at “Vivax” use. At “Asepta” and “Wood balm” series use this index was 4.70 and 4.10 roubles, respectively. Conclusions. The use of medicamentous complexes “Asepta”, “Vivax” and “Wood balm” promote the disappearance of the parodontitis signs. The use of such series as “Asepta” helps to achieve faster and long anti-inflammatory effect. The use of this complex expediently also from the economic point of view.

Background. The urgency of a problem of the infections caused by Gram-positive microorganisms all over the world constantly increases. Staphilococcus cause the considerable part of the outpatient and nosocomial bacteriemia, pneumonia, infections of skin, soft tissues, bones and joints. Methods. 48 strains of Staphylococcus aureus and 51 strains of Staphylococcus epidermidis isolated from operation and postoperative wounds, the upper respiratory ways of medical staff and an environment of surgical units were studied. The method of polymerase chain reaction in a mode of “real time” was used to define the virulence markers with the sets of specific primers to three genes of pathogenicity fnbрА, fnbрВ and Luc PVS) and to the meticillin-resistant gene (mec A). Results. In dynamics the increase of frequency of detection of pathogenicity genes and geneovariant combinations is noted. At S. aureus spp. pathogenicity has been genetically determined in 81.8 %, at S. epidermidis spp. - in 4 % of cases (isolated from operation wounds). S. epidermidis spp. isolated from surgical medical staff had pathogenicity genes in 14.3 %, and S. aureus spp. - in 85 % of cases. In postoperative wounds genetic determinants were found with less frequency. In microflora of the environment of surgical hospitals pathogenicity genes are allocated only in 11.1 % of S. epidermidis spp. The meticillin-resistance gene is found out at both kinds of Staphilococcus isolated from various biotops. Conclusion. The analysis of prevalence of genetic determinants confirms the growth of pathogenicity of the clinical isolates of S. epidermidis and S. aureus in the course of the wound infections and also confirms the fact of horizontal transfer of gene Luc PVS. Stability genes to meticillin at S. epidermidis spp. were found more often, especially at strains isolated of biotests that confirms the role of S. epidermidis in transfer of the mobile genetic element mecА of S. aureus.

Background. A research objective: the analysis of the morphometric laws of the bone tissue of the dental-mandibular segments of incisors. Methods. 174 anatomic mandibular preparations of people of mature age of both sexes with physiological occlusion were studied. Preparations were sawed on 14 segments on intertooth septs in vestibular-lingual direction. Each segment on identical distance from the object was photographed in medial and distal norms. Increase necessary for the subsequent mathematical calculations was defined by the comparison of the sizes of the marked sites on the sample and in a photo. Results. The height of dental-mandibular segments from the alveolar crest to the basis was 36.27±0.64 mm. The height of the alveolar part of every dental-mandibular segment corresponded to the length of the same named tooth root and varied in a wide range. The areas of the dental-mandibular segments, and also the area of spongy and compact substances of medial and lateral incisors did not differ reliably. Conclusions. The areas of dental-mandibular segments as well as the areas of separate structures of the bone tissue have no reliable difference. The thickness of compact substance reliably increases from the top part of dental-mandibular segments in a direction to their basis. The greatest thickness of spongy substance is observed in the bottom part of the vestibular part of dental-mandibular segments that is connected with the presence of mental ledge.

Background. At the existing tendency to morbidity growth and increase of prevalence of risk factors of the obliterating atherosclerosis of the lower limbs the improving of conservative methods of treatment is more and more actual. As the important components of this direction are the correction of the endothelial dysfunction and stimulation of the neoangiogenesis. Methods. 40 patients with acute and chronic ischemia of the lower limbs due to the obliterating atherosclerosis were examined. The stress-induced system indicators - nitrogen oxide, thermal shock proteins, endothelial factor of growth, Bcl-2 proteins - after reconstructive-regenerative surgeries on the main arteries and without them (control group) - were studied. Results. The level of the thermal shock proteins and the nitrogen oxide metabolits in patients’ blood after the surgical treatment has decreased. The pilot studying of neoangiogenesis markers has shown the significant change of the endothelial growth factor comparing with the control group. Conclusions. The revealed authentic tendencies in change of stress-inducible system indicators prove their direct influence on the mechanisms of immediate and long-term adaptation to ischemic stress and reperfusive answer in the postoperative period.

Background. At doing of the demountable prosthesis the most widespread basic material are acrylic plastics which lacks are the possibility of the microbe growth and the incomplete polymerization leading to the residual maintenance of the monomer in the prosthesis. Methods. On the basis of the clinical analysis and gums’ biopsies at 63 patients of 60-74 years old the parameters of the local immune homeostasis depending on a kind of a basic material of the demountable plate prosthesis - acrylic plastics Meliodent (Germany), Ftorax (Ukraine) and Basis (Japan) were investigated. Results. All examined patients had gingivitis and parodontitis of mild and moderate severity level. The analysis of the biopsies has shown considerable changes of structure of cellular cooperation of a mucous membrane in comparison with the control in all follow-up terms. These changes were accompanied by the increase in proliferative epithelium activity. More expressed reaction is registered on the prosthesis made of plastic of firm Ftorax. Direct strong correlation between the quantity of Langerhans cells and iodine value Svrakova is revealed at use of the acrylic plastic Ftorax and direct weak correlation - at use of the acrylic plastics of firms Meliodent and Basis. Conclusions. Expressiveness of inflammatory process in the mouth mucous membrane is caused by the changes of a quantitative parity of the elements supporting the immune homeostasis. Clinical and morphological changes of an orthopedic bed have appeared more expressed at using of the prosthesis made of plastic Ftorax that allows to recommend the plastics of other manufacturers as basic materials.

Background. The WHO has included teeth caries in the six illnesses of the present which prophylaxis is the most actual problem of a medical science and public health services. Methods. For the purpose of the complex analysis of the condition of phosphor-calcium exchange at children with caries the examination of 104 patients of 7-14 years old with compensated and subcompensated disease forms (the basic group) and 20 healthy children with intact teeth (control group) was done. The research material was the blood serum and mixed non-stimulated saliva in which the concentration of the general and ionized calcium and inorganic phosphate were estimated. In blood serum also the level of calcitonin, osteocalcin, parat hormone and 25-hydroxy vitamin D₃ was calculated. Results. In blood serum of all patients the maintenance of the general calcium and phosphorus was within reference limits. However at children with caries requiring therapy the relative insufficiency of the general calcium and statistically significant decrease in the ratio of the ionized calcium and inorganic phosphorus are revealed. The concentration of the ionized calcium in saliva was significantly higher at children requiring sanitation of teeth. At them considerable change of the ratio “calcium: phosphorus” is found. At all children with caries the hyperproduction of osteocalcin and decreased level of 25-hydroxy vitamin D₃, the direct moderate correlation between calcitonin level and 25-hydroxy vitamin D₃ is revealed. At complex treatment by calcium and vitamin D₃ in 6 months there was statistically significant increase in blood of the general and ionized calcium and 25-hydroxy vitamin D₃ and also normalized the local level of calcium and its ratio to phosphorus. Conclusions. Infringement in calcium-phosphoric balance leads to the mineralization lesion of enamel and reduces the resistance of the tooth tissues to adverse influence of the oral liquid. Treatment of children with subcompensated caries of the combined calcium preparation leads to the normalization of phosphor-calcium exchange.

Background. According to the World Health Organization up to 75 % of the population in various regions of the Earth suffer from the partial teeth absence. Needs in orthopedic treatment by demountable prosthesis in such patients is 33-58%. The research objective is pathogenetic choice substantiation of the basic stomatologic materials on the basis of the analysis of the immune homeostasis parameters of a mucous membrane of a mouth. Methods. 36 men of 25-85 years old for the occlusive rehabilitation of whom the acrylic and nylon prosthesis were used are examined. The control - 12 patients of 20-85 years old with a similar dental pathology but requiring preliminary surgical preparation for prosthetics. Qualitative and quantitative characteristics of the morphological substratum providing an immune homeostasis of a mucous membrane of a mouth in the field of an orthopedic bed are studied. Results. Together with the orthopedic stomatitis there was a quantity substantial growth of intraepithelial T-lymphocytes and increase in proliferative epithelial activity. At use of the acrylic materials the quantity of antigen-presenting cells statistically increased, in an alteration zone the maintenance of intraepithelial lymphocytes increased. Conclusions. Orthopedic treatment with use of demountable prosthesis causes changes of parameters of an immune homeostasis of a mucous membrane of a mouth and character of these changes (clinical and morphological) is defined by the chemical components contained in basic plastics. At using of the nylon prosthesis the changes of the immune homeostasis of a mucous membrane of a mouth are less expressed in comparison with similar indicators at use of the acrylic plastics.

Background. An important aspect of occurrence of early complications of dental implantation and inflammation in the implantation area is integrity of a connecting tissue surrounding it while its injury influences the balance of the tissue metalloproteinase-1 inhibitor (TIMP1) and matrix metalloproteinase (MMPs) 8 and 9. Methods. 80 patients at the age of 30-60 years old who underwent dental implantation were examined. In 70 cases the postoperative period had no complications (1^st group); at 10 cases there were early complications - an edema and hyperemia of the soft tissues (2^nd group). In blood and the mixed oral liquid the levels of MMP-8, MMP-9 and TIMP1 were determined. For the control authors investigated the blood and the oral liquid of 20 practically healthy people. Results. Statistically significant increase of the systemic level of ММР-8 is revealed, MMP-9 and TIMP1 has been considerably raised at patients of 2nd group. At patients with not complicated postoperative period local and systemic increase of concentration of MMP-9 and local increase of concentration of TIMP1 is found. Conclusions. Studying of qualitative and quantitative characteristics of ММРs and their inhibitors is a perspective direction of basic researches which will allow developing the new approaches to diagnostics and treatment of complications at dental implantation.

Background. Caries in children undergoing the orthodontic treatment is caused by the complex of adverse factors the most important of which is the microflora of the tooth plaque. Methods. 47 patients of 9-15 years with дистальной окклюзией during the orthodontic treatment in different follow-up period are examined: in 1, 6 and 18 months. Authors studied features of qualitative and quantitative structure of the microbiocenosis of the tooth plaque and estimated the level of sensitivity of microbiota representatives to antiseptics. Results. From the tooth plaque biomaterial in 25 % of cases allocated mycosis of the type Candida albicans together with the high level of microorganisms of the caries-inducing and associative groups (Streptococcus, Enterococcus, Staphylococcus, Neisseria, Micrococcus, Corynebacterium, Klebsiella). The majority of strains have shown the expressed resistance to 0.01 % miramistin. The highest level of the minimum overwhelming concentration in relation to the cultures of S. aureus, S. epidermidis, S. haemolyticus and C. albicans was defined for 0.1 % chlorine hexidine bigluconate. Conclusions. The obtained data allowed showing that orthodontic treatment of children by fixed equipment promotes constant increase in the level of the tooth plaque microbiota and is the important risk factor of caries. Representatives of the microbiota during the treatment can adapt for the specific conditions of existence and increase resistance to some kinds of the antiseptic agents.

Background. One of the important problems in stomatology is introduction in practice of the objective criteria of the estimation of the treatment quality developed on the basis of the systematization of the modern tactics approaches to the treatment and unification of the optimum modes of the treatment-and-prophylactic care. Methods. In the Udmurt Republic algorithms of diagnostics and treatment of inflammatory parodont diseases are developed and introduced in practice. The dynamics of clinical indicators by the results of the analysis of 370 medical cards (the form № 043/u) of the patients who underwent the treatment for chronic generalized parodontitis in municipal stomatologic clinics of different level was estimated. The dynamic evaluation of quality of life was done by the questionnaire OHIP-14-RU “Profile of influence of stomatologic health”. Results. The use of the algorithms at parodontitis treatment has allowed improving the index of oral cavity hygiene on the average on 57.2 %, the papillary-marginal-alveolar index - on 85.9 %, the bleeding index - on 95.5 %. The most expressed clinical effect was reached at providing the specialized stomatologic care. In the clinics of the qualified stomatologic care the use of algorithms has allowed to improve the results of treatment of all parodontitis forms whereas in the specialized clinics the introduction of algorithms has allowed to improve clinical indicators only at moderate and severe parodontitis. In high-specialized medical institutions the introduction of algorithms has more essentially affected the results of treatment of the severe parodontitis. Conclusions. The introduction in municipal clinics of the Udmurt Republic of algorithms of diagnostics and treatment, techniques and criteria of the estimation of efficiency of treatment at patients with parodont inflammatory diseases has allowed to systematize the volume of diagnostic and medical manipulations, to find the objective indicators of the parodontal care, to improve the quality of treatment of chronic generalized parodontitis and to raise the quality of life of patients.

The author suggests for discussion the concept of the organization of the orthodontic help to the population of the Far Eastern federal region which main goal is the increase of the efficiency of orthodontic services at rational use of resources of public health services. The basic priorities of the concept are the creation of organizational structure of the orthodontic help according to the levels of its providing, resource, technological and normative legal maintenance as well as the monitoring and efficiency audit.

The techniques of rehabilitation of patients with severe atrophy of alveolar recessus are described as well as the facial polytrauma, and also at jaw resections due to tumors. Experience on introduction of methods of preorthopedic regenerative surgery in stomatology is generalized. In a number of clinics of Russia and the near abroad in 2006-2012 3000 patients underwent more than 3500 implantations, more than 560 bone blocks transplantations and 940 sinus-lifting surgeries. Combined implantation and sinuslifting are done in 623 cases. Since September, 2012 more than 100 angular implants Co-Axis and 9 implants Zygomatic 55° in the combination with platform-implants 12° and 24° were put. 60 % of patients on the top jaw and 80 % - on bottom underwent the immediate fixation of the provisory orthopedic constructions with implants support. The requirements to the experts’ team who are engaged in preorthopedic regenerative surgery and multiple stage stomatologic rehabilitation are discussed.

Background. In the majority of programs on prophylaxis of stomatologic diseases the main attention is given to the children and young people, prophylaxis among elderly at municipal level is not widely spread. Methods. On the basis of an original questionnaire the stomatologic education level of 98 patients if the stomatologic polyclinic № 5 of Krasnoyarsk is estimated: 1^st group - 56 cases at the age of 45-64 years, 2^nd group - 42 patients at the age of 65 years and more old. Results. Patients aged more than 65 y. o. were less informed on possibilities of preservation of health of an oral cavity. Index of КПУ in aged group increased due to the remote teeth, the quantity of carious and the sealed up teeth was at one level. Conclusions. The principal cause of removal of teeth in people older than 45 years old was parodontal diseases. Patients of advanced age have features of perception of the new information and their base knowledge in this area does not provide due stomatologic health. The development of strategy of providing of the stomatologic care is necessary for the elderly population, one of which obligatory components is the educational work considering the specific features of senior patients.

The short article on the results of treatment by levocetirizin (xyzal) and HLA-typing of the 63 patients with eczema. The raised frequency of finding of antigens HLA А28, HLA В21 and HLA Сw2 is revealed and the frequency of finding of antigens HLA А1, HLA В13, HLA В16 and HLA В18 is decreased. Clinical efficiency of xyzal is registered in 93.7 % of follow-up: at 59 patients the remission or the condition improvement are shown.

The direct method of manufacturing of fitting and if it’s necessary temporal teeth restorations of self-hardening plastic which can be used for producing of ideally fitting and having an exact contour vinirs is described. The minimum time and materials are required. As this method does not demand the teeth preparation it allows the patient and the stomatologist to study visually the plan of treatment which can have the alternative decisions.

The paper analyzes the results of treatment of children with liver and spleen ruptures in case of non-penetrating intraabdominal injuries in Primorsky Krai regional medical centres (81 cases) and demonstrates the advantages of sonography over laparocentesis in accuracy diagnosing the abdominal cavity organ traumas, which does not exclude this method from being used in the regional medical centres. The authors believe the conservative therapy and organ-saving surgeries to be a method of choice to be used in case of traumas in parenchymatous organs, even under the intra-abdominal bleeding conditions. This approach is likely to be introduced in specialized hospital department, given the monitoring at the children resuscitation beds.

Background. Absence of accessible and objective methods for studying of the dimensional neuron organization of various mediator usage leads to inconsistent estimations of the type of the relations between these cells in unique or multiple nucleus in any brain formation. Methods. On consecutive cuts of the longitudinal brain the neural structure of reticular lateral nucleus is studied by methilene blue coloring and also by the methods for revealing of norepinephrinergic and nitroxodergic neurons. The received nucleus images displayed on the monitor screen then were combined and on the basis of the received data the topochemical neuron carting was done. Results. At combination of the nucleus images received on the consecutive cuts after their coloring by the proper methods not only the features of the dimensional neuronal organization were revealed but also rather distinctively the differences of the form, the sizes and numbers of each cell population. Conclusions. The suggested method is accessible and simple in use, allows obtaining quickly the objective data for exact and detailed topochemical carting of the various mediator systems in one or several structural brain formations.

Background. Simple, reliable and predicted obturation of the tooth root channels is the important component of the endodontic treatments. Methods. The frequency of microleaking and average depth of penetration of dye after the channels sealing by the method of lateral condensation by the obturation system RealSeal-Resilon and by gutta-percha and AH-Plus sealer on the removed teeth are studied. The acoustic and optical microscopy and also radiological research of samples are done. Results. The frequency of microleaking of the root seals at system RealSeal-Resilon use was 10.2 %, the depth of penetration of dye -1.9±0.2 micron (for AH-Plus - 23 % and 2.8±0.5 micron respectively). On radiological data small defects of contact at use of a new material were found in 12.5% of cases and after use of polymeric pitch AH-Plus - in 46.9 % of cases. Conclusions. Better obturation of the root channels was reached at system RealSeal-Resilon use in a combination with the composite hermetic of double hardness and resilon shtifts due to the high density of the material and its closer integration with dentin.

Background. The work purpose was in the description of the mathematical analysis method of optic-spatial mnestic processes in students at interaction with the computer. Methods. 126 students at the age from 17 till 37 years old of different courses of internal and correspondence branches have taken part in the research (78 female and 48 - male). Middle age of the female examinees was 22.67 years, male’s - 21.58 years old. Students played the position computer game. The parametres quantitatively characterising the short-term components of working memory in three sessions of game were estimated. Results. The quantity of spatially-visions placed in the short-term incidental buffer in 72 % of examinees did not exceed three. Only in 3 % of cases the quantity of the cognitive references was within 4-6, Conclusions. The received results in general are coordinated with the multicomponent model of working memory. In the course of the computer game students used its short-term components. The quantity of spatially-visions placed in the short-term incidental buffer of memory in 96 % of students does not exceed four.

In article the specific features of the organization and providing of the dental help to the inhabitants of Primorski Krai in the first years of the Soviet power are shown. It is found out, that this kind of medical aid was perceived by the power as one of the elements of social preferences and privileges for separate categories of the population. In this connection, it has been organized for one social group - people of wage labor and also the members of their families who were the participants of insurance cash desks. Meanwhile, the constantly increasing volumes of the medical dental help did not lead to decrease in the requirement for this kind of medical services that has pushed the power to introduce municipal programs of prophylaxis of teeth caries at children and teenagers as well as the workers of the industrial enterprises. The lack of the state financing, the interdiction for direct payments of the population, a great demand on dental services have forced to refuse more expensive but more effective materials and treatment techniques. However the considerable part of the Far Eastern population had no possibility to use a public network of dental services.